

AQUACULTURE
by Bio-Angle Vacs
Our Vision
The Best In Class for Innovative Animal Vaccines
Our Mission
To support global food security sustainability agenda
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To produce safe, efficacious and affordable veterinary products that improve the health of livestock and aquaculture animals by leveraging on new technology and innovation
To improve farmers’ productivity and income​
Aquaculture
(Fish)
Global fisheries and aquaculture production in 2022 was 223.2 million tonnes with an estimated value of USD 452 billion.
Aquaculture accounted for 51 percent (94 million tonnes) and valued at USD 296 billion.
30.8 million tonnes or 37.5% of the world’s farmed food fish production, with major producing countries are China, India, Indonesia, Vietnam, Philippines, Bangladesh, Egypt,Norwayand Chile.
USD 452B
Global Fish Production
USD 296B
Aquaculture Population Value
37.5%
World’s Farmed Food Fish

BACTERIAL
DISEASES
IN AQUACULTURE
Marine fish
VIBROSIS
Scale Drops
Fin Necrosis

Skin Ulceration
Vibrio spp. :
V. salmonicida,
V. vulnificus,
V.harveyi alginolyticus,
and V. parahaemolyticus
Mortality Rate: 50%

DISEASE MANAGEMENT

ANTIBIOTIC
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Antibiotics are commonly used to prevent and control bacterial diseases in aquaculture (Assane et al., 2019)
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Antibiotic abuse has affected the fish microbiome because antibiotics can target commensal bacteria that support fish health and immune function (Carlson et al., 2017)
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The accumulation of antibiotic waste in the food chain can harm humans and the environment (Vignesh et al., 2011)
VACCINATION
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Vaccination - an alternative to prevent various bacterial diseases in aquaculture
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Vaccines are antigens that have been weakened or inactivated to actively stimulate the fish's immunity
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Fish vaccines in ASEAN - Limited coverage; different serotypes

Oral Vaccination
No stress
Practical for mass vaccination
Requires no specialized facilities

Induce local and systemic immune response
Injection Vaccination
Allows direct stimulation of the immune response
Not suitable for large-scale vaccination.
Causes stress and injury to fish

OUR SOLUTION
INNOVATIVE SOLUTION FEED-BASED VACCINES
ViVac
AGAINST VIBRIOSIS
(FOR MARINE FISH)
A newly developed Feed Based Vaccine where the active component/antigen is incorporated into commercial feed and administered as part of the feeding regime. The feed-based vaccine enhances fish immunity, particularly against Vibrio spp. that are found frequently in the marine fish cultures.
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It is administered orally through feeding and reported to improve fish survival from 50% to at least 80%.
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Administration that is free-of-stress
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Easy to apply, highly suitable for mass aquaculture activity and smallholdings
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Effective to all size of fish
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Less time consuming
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Low in labor cost

Feed-Based Vaccine
Prevent from Vibrosis by 80% Efficacy
Suitable for fish of all sizes and easy to administer

OUR STUDIES
LABORATORY CHALLENGE STUDY - VIVAC
Immune protection test : V. harveyi

72.5% survival
Immune protection tests: V. alginolyticus

70% survival
Immune protection tests:
V. parahaemolyticus

92.5% survival
FIELD STUDY - VIVAC


Grouper (Epinephelus sp.)
Fish cage, Langkawi, Malaysia
Fish growth achievements


Seabass (Lates calcarifer)
Fish growth achievements
Fish cages,Pulau Ketam, Malaysia
